HPO
Db Link Name Definition Comment Is a
HPO HP:0500053 Retinopathy of prematurity stage 4 "Scar tissue that forms a continuous sheet coming up from the edge of the vascularized retina. This scar tissue can grow toward the vitreous base/posterior lens capsule resulting in traction, distortion, and even detachment." [ISBN:978-3-319-52190-9] Stage 4 can occur after treatment (unlike stages 1-3) and may be accelerated by the absence of vascular endothelial growth factor posttreatment leading to an accelerated cicatricial phase. HP:0500049
HPO HP:0500054 Retinopathy of prematurity stage 4a "A detachment that involves the peripheral retina that does not extend into the macula." [ISBN:978-3-319-52190-9] HP:0500053
HPO HP:0500055 Retinopathy of prematurity stage 4b "A detachment that involves the peripheral retina that involves the macula itself. The detachment usually starts in the temporal periphery although can also involve the nasal retina as well." [ISBN:978-3-319-52190-9] HP:0500053
HPO HP:0500056 Retinopathy of prematurity stage 5 "Funnel detachment from the retina with generally traction in all four quadrants." [ISBN:978-3-319-52190-9] HP:0500049
HPO HP:0500057 Retinopathy of prematurity stage 5a "An open funnel detachment of the retina with generally traction in all four quadrants." [ISBN:978-3-319-52190-9] HP:0500056
HPO HP:0500058 Retinopathy of prematurity stage 5b "A closed funnel detachment of the retina with generally traction in all four quadrants." [ISBN:978-3-319-52190-9] HP:0500056
HPO HP:0500059 Retinopathy of prematurity zone I "Retinopathy which extends from the center of the optic disc to twice the distance from the center of the optic disc to the center of the macula." [ISBN:978-3-319-52190-9, PMID:16009843] HP:0500049
HPO HP:0500060 Retinopathy of prematurity zone II "Retinopathy which extends centrifugally from the edge of zone I to the nasal ora serrata." [ISBN:978-3-319-52190-9, PMID:16009843] HP:0500049
HPO HP:0500061 Retinopathy of prematurity zone III "Retinopathy which is a residual crescent of retina anterior to zone II." [ISBN:978-3-319-52190-9, PMID:16009843] HP:0500049
HPO HP:0500062 Retinopathy of prematurity plus "Venous dilatation and arteriolar tortuosity of the posterior retinal vessels and may later increase in severity to include iris vascular engorgement, poor pupillary dilatation (rigid pupil), and vitreous haze. This definition has been further refined in the later clinical trials in which the diagnosis of plus disease could be made if sufficient vascular dilatation and tortuosity are present in at least 2 quadrants of the eye." [PMID:16009843] HP:0500049
HPO HP:0500063 Retinopathy of prematurity pre-plus "As vascular abnormalities of the posterior pole that are insufficient for the diagnosis of plus disease but that demonstrate more arterial tortuosity and more venous dilatation than normal." [PMID:16009843] Over time, the vessel abnormalities of pre-plus may progress to frank plus disease as the vessels dilate and become more tortuous. {xref="PMID:16009843"} HP:0500049
HPO HP:0500064 Retinopathy of prematurity threshold "A retinopathy with a 50% likelihood of progressing to retinal detachment. Threshold disease is considered to be present when stage 3 retinopathy of prematurity (ROP) is present in either zone I or zone II, with at least 5 continuous or 8 total clock hours of disease, and the presence of plus disease." [ISBN:978-3-319-52190-9] HP:0500049
HPO HP:0500065 Retinopathy of prematurity prethreshold "High risk patients who were in Zone 1 (no Plus or stage 3) or Zone 2 with Plus or stage 3 but not both." [ISBN:978-3-319-52190-9] HP:0500049
HPO HP:0500066 Latent myopia "The difference between total and manifest myopia." [ORCID:0000-0003-0986-4123] HP:0000545
HPO HP:0500069 Paralytic ectropion "A type of ectropion associated with orbicularis muscle weakness caused by cranial nerve VII palsy." [ISBN-13:9781416029076, ORCID:0000-0003-0986-4123] HP:0000656
HPO HP:0500070 Conjunctival dermolipoma "A conjuctival lesion composed of adipose tissue and dense connective tissue. Such choristomas of dermal elements are normally found at the outer canthus, and have a gelatinous appearance. Classically, there is an indistinct posterior border (with the lesion frequently extending into the orbit) and a well-demarcated anterior border several millimetres posterior to the limbus." [ORCID:0000-0003-0986-4123] HP:0000502
HPO HP:0500072 Absolute eccentric fixation "Eccentric fixation in which the angle of eccentricity equals the objective angle of deviation." [ORCID:0000-0003-0986-4123] HP:0025549
HPO HP:0500073 Abnormal ocular alignment "Any deviation from the normal ocular alignment." [ORCID:0000-0001-7941-2961] HP:0000496
HPO HP:0500074 Dissociated vertical deviation "An incomitant tendency for an occluded eye to elevate and extort which resolves on uncovering." [ISBN-13:978-0199679980] Dissociated vertical deviation (DVD) occurs when the level of illumination received by either eye is reduced sufficiently and as a result eye deviates progressively upwards, but reverts to its original position when the level of illumination returns to normally acceptable levels. It may sometimes be so asymmetrical as to be virtually unilateral and is associated with heterotropia usually of early onset. {xref="ISBN-13:978-0199679980", xref="ORCID:0000-0003-0986-4123"} HP:0500073
HPO HP:0500075 Dissociated horizontal deviation "A change in horizontal ocular alignment, unrelated to accommodation, that is brought about solely by a change in the balance of visual input from the two eyes." [PMID:18427617] HP:0500073
HPO HP:0500076 Alternating hypertropia "A type of vertical tropia in which, when one eye is fixing, the other eye is deviated upwards." [ORCID:0000-0003-0986-4123] HP:0025586
HPO HP:0500077 Alternating hyperphoria "A type of vertical phoria in which, in dissociation, the occluded eye deviates upwards." [ORCID:0000-0003-0986-4123] HP:0025585
HPO HP:0500078 Alternating hypotropia "A type of vertical tropia in which, when one eye is fixing, the other eye is deviated downwards." [ORCID:0000-0003-0986-4123] HP:0025584
HPO HP:0500079 Alternating hypophoria "A type of vertical phoria in which, in dissociation, the occluded eye deviates downwards." [ORCID:0000-0003-0986-4123] HP:0031725
HPO HP:0500081 Pseudophakia "The term pseudophakia refers to having an artificial lens implanted after the natural eye lens has been removed. During cataract surgery the natural cloudy lens is replaced by an pseudophakia intraocular lens (IOL)." [PMID:28358301] HP:0000517