| HPO |
HP:0001699 |
Sudden death |
"Rapid and unexpected death." [HPO:probinson] |
— |
HP:0025142 |
| HPO |
HP:0001700 |
Myocardial necrosis |
"Irreversible damage to heart tissue (myocardium) due to lack of oxygen after a heart attack (myocardial infarction)." [PMID:20405318] |
— |
HP:0001637 |
| HPO |
HP:0001701 |
Pericarditis |
"Inflammation of the sac-like covering around the heart (pericardium)." [HPO:probinson] |
— |
HP:0001697, HP:0045073 |
| HPO |
HP:0001702 |
Abnormal tricuspid valve morphology |
"Any structural anomaly of the tricuspid valve." [HPO:probinson] |
— |
HP:0006705 |
| HPO |
HP:0001704 |
Tricuspid valve prolapse |
"One or more of the leaflets (cusps) of the tricuspid valve bulges back into the right atrium upon contraction of the right ventricle." [HPO:probinson] |
— |
HP:0001702 |
| HPO |
HP:0001705 |
Right ventricular outlet tract obstruction |
"An obstruction to the forward flow of blood in the outflow tract of the right ventricle." [PMID:30038501] |
— |
HP:0033118 |
| HPO |
HP:0001706 |
Endocardial fibroelastosis |
"Diffuse thickening of the ventricular endocardium and by associated myocardial dysfunction" [PMID:23109776] |
— |
HP:0004306 |
| HPO |
HP:0001707 |
Abnormal right ventricle morphology |
"An abnormality of the right ventricle of the heart." [HPO:probinson] |
The function of the right ventricle is to receive blood from the right atrium and to eject blood into the pulmonary artery. |
HP:0001713 |
| HPO |
HP:0001708 |
Right ventricular failure |
"Reduced ability of the right ventricle to perform its function (to receive blood from the right atrium and to eject blood into the pulmonary artery), often leading to pitting peripheral edema, ascites, and hepatomegaly." [HPO:probinson] |
— |
HP:0033118 |
| HPO |
HP:0001709 |
Third degree atrioventricular block |
"Third-degree atrioventricular (AV) block (also referred to as complete heart block) is the complete dissociation of the atria and the ventricles. Third-degree AV block exists when more P waves than QRS complexes exist and no relationship (no conduction) exists between them." [PMID:21841933] |
— |
HP:0001678 |
| HPO |
HP:0001710 |
Conotruncal defect |
"A congenital malformation of the outflow tract of the heart. Conotruncal defects are thought to result from a disturbance of the outflow tract of the embryonic heart, and comprise truncus arteriosus, tetralogy of Fallot, interrupted aortic arch, transposition of the great arteries, and double outlet right ventricle." [HPO:probinson] |
— |
HP:0011563, HP:0011603 |
| HPO |
HP:0001711 |
Abnormal left ventricle morphology |
"Any structural abnormality of the left ventricle of the heart." [HPO:probinson] |
— |
HP:0001713 |
| HPO |
HP:0001712 |
Left ventricular hypertrophy |
"Enlargement or increased size of the heart left ventricle." [MP:0002625] |
— |
HP:0001711, HP:0001714 |
| HPO |
HP:0001713 |
Abnormal cardiac ventricle morphology |
"An abnormality of a cardiac ventricle." [HPO:probinson] |
— |
HP:0001627 |
| HPO |
HP:0001714 |
Ventricular hypertrophy |
"Enlargement of the cardiac ventricular muscle tissue with increase in the width of the wall of the ventricle and loss of elasticity. Ventricular hypertrophy is clinically differentiated into left and right ventricular hypertrophy." [HPO:probinson] |
— |
HP:0001713 |
| HPO |
HP:0001716 |
Wolff-Parkinson-White syndrome |
"A disorder of the cardiac conduction system of the heart characterized by ventricular preexcitation due to the presence of an abnormal accessory atrioventricular electrical conduction pathway." [HPO:probinson] |
— |
HP:0004309 |
| HPO |
HP:0001717 |
Coronary artery calcification |
"An accumulation of calcium and phosphate in arteries with mineral deposits in the intimal or medial layer of the vessel wall in a coronary artery." [HPO:probinson] |
— |
HP:0003207, HP:0006704 |
| HPO |
HP:0001718 |
Mitral stenosis |
"An abnormal narrowing of the orifice of the mitral valve." [DDD:dbrown] |
— |
HP:0031481 |
| HPO |
HP:0001719 |
Double outlet right ventricle |
"Double outlet right ventricle (DORV) is a type of ventriculoarterial connection in which both great vessels arise entirely or predominantly from the right ventricle." [HPO:probinson, PMID:10798433] |
During the development of the heart, the outflow tract initially connects exclusively with the primitive right ventricle and must undergo extensive remodelling to divide into a separate pulmonary artery and aorta; subsequently, there is continued remodelling to establish direct continuity from the left ventricle to the aorta. DORV encompasses a wide spectrum of anatomic arrangements and pathophysiologic disturbances. At one end of the spectrum, it mimics tetralogy of Fallot in the presence of pulmonary stenosis, or a large ventricular septal defect (VSD) in the absence of such stenosis. At the other end of the spectrum, it behaves like transposition of the great arteries with a VSD. |
HP:0001710, HP:0011723 |
| HPO |
HP:0001722 |
High-output congestive heart failure |
"A form of heart failure characterized by elevated cardiac output. This may be seen in patients with heart failure and hyperthyroidism, anemia, pregnancy, arteriovenous fistulae, and others." [HPO:curators] |
— |
HP:0001635 |
| HPO |
HP:0001723 |
Restrictive cardiomyopathy |
"Restrictive left ventricular physiology is characterized by a pattern of ventricular filling in which increased stiffness of the myocardium causes ventricular pressure to rise precipitously with only small increases in volume, defined as restrictive ventricular physiology in the presence of normal or reduced diastolic volumes (of one or both ventricles), normal or reduced systolic volumes, and normal ventricular wall thickness." [HPO:probinson, PMID:17916581] |
Historically, systolic function was said to be preserved in RCM, but is rare for contractility to be truly normal. Restrictive physiology can occur in patients with end-stage hypertrophic and DCM. |
HP:0001638 |
| HPO |
HP:0001724 |
obsolete Aortic dilatation |
— |
— |
— |
| HPO |
HP:0001726 |
obsolete Increased prevalence of valvular disease |
— |
— |
— |
| HPO |
HP:0001727 |
Thromboembolic stroke |
"A cerebrovascular accident (stroke) that occurs because of thromboembolism." [HPO:probinson] |
— |
HP:0001907 |
| HPO |
HP:0001730 |
Progressive hearing impairment |
"A progressive form of hearing impairment." [HPO:probinson] |
— |
HP:0000365 |