| HPO |
HP:0005177 |
Premature arteriosclerosis |
"Arteriosclerosis occurring at an age that is younger than usual." [HPO:probinson] |
— |
HP:0002634 |
| HPO |
HP:0005178 |
Complete heart block with narrow QRS complexes |
"A type of third degree heart block in which the escape rhythm arises at the atrioventricular node, which produces a narrow QRS complex." [] |
— |
HP:0001709 |
| HPO |
HP:0005180 |
Tricuspid regurgitation |
"Failure of the tricuspid valve to close sufficiently upon contraction of the right ventricle, causing blood to regurgitate (flow backward) into the right atrium." [HPO:probinson] |
This term should not be applied to Ebstein's anomaly of the tricuspid valve (see HP:0010316). |
HP:0031651 |
| HPO |
HP:0005181 |
Premature coronary artery atherosclerosis |
"Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries before age of 45." [PMID:28070240] |
— |
HP:0001677 |
| HPO |
HP:0005182 |
Bicuspid pulmonary valve |
"The presence of a bicuspid pulmonary valve." [HPO:probinson] |
The pulmonary valve normally has three cusps (flaps), that is, it is normally tricuspid. |
HP:0031566 |
| HPO |
HP:0005183 |
Pericardial lymphangiectasia |
"An abnormal dilatation of lymph vessels in the pericardium." [PMID:18391124] |
— |
HP:0001697, HP:0031842 |
| HPO |
HP:0005184 |
Prolonged QTc interval |
"A longer than normal interval (corrected for heart rate) between the Q and T waves in the heart's cycle. Prolonged QTc can cause premature action potentials during late phase depolarizations thereby leading to ventricular arrhythmias and ventricular fibrillations." [PMID:24097136] |
— |
HP:0001657 |
| HPO |
HP:0005185 |
Global systolic dysfunction |
"A reduced ejection fraction and an enlarged left ventricle chamber, the latter by an increased resistance to filling with increased filling pressures. Systolic dysfunction is clinically associated with left ventricular failure in the presence of marked cardiomegaly." [PMID:24173273, PMID:7713107] |
— |
HP:0006673 |
| HPO |
HP:0005186 |
Synovial hypertrophy |
— |
— |
HP:0005262 |
| HPO |
HP:0005187 |
Progressive joint destruction |
— |
— |
HP:0001367 |
| HPO |
HP:0005190 |
Proximal finger joint hyperextensibility |
— |
— |
HP:0001187 |
| HPO |
HP:0005191 |
Congenital knee dislocation |
— |
— |
HP:0004976 |
| HPO |
HP:0005193 |
Restricted large joint movement |
— |
— |
HP:0001376 |
| HPO |
HP:0005194 |
Flattened metatarsal heads |
"Abnormally flat shape of the heads of the metatarsal bones." [HPO:probinson] |
The metatarsal heads articulate with the proximal phalanges of the toes. |
HP:0001832 |
| HPO |
HP:0005195 |
Polyarticular arthropathy |
— |
— |
HP:0003040 |
| HPO |
HP:0005197 |
Generalized morning stiffness |
"A sensation of stiffness in the joints that occurs following waking up in the morning." [HPO:curators] |
— |
HP:0001387 |
| HPO |
HP:0005198 |
Stiff interphalangeal joints |
"Interphalangeal joint stiffness is a perceived sensation of tightness in the interphalangeal joints when attempting to move them after a period of inactivity." [HPO:curators] |
— |
HP:0001387, HP:0005262 |
| HPO |
HP:0005199 |
Aplasia of the abdominal wall musculature |
"Absence of the abdominal musculature." [HPO:probinson] |
— |
HP:0010318 |
| HPO |
HP:0005200 |
Retroperitoneal fibrosis |
— |
— |
HP:0002585 |
| HPO |
HP:0005201 |
Anomalous splenoportal venous system |
— |
— |
HP:0031941 |
| HPO |
HP:0005202 |
Helicobacter pylori infection |
"A recurrent infection of the GI tract with helicobacter pylori, a gram-negative, microaerophilic bacterium usually found in the stomach." [PMID:23652324] |
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes approximately half of the human population, but only causes overt gastric disease in a subset of infected hosts. |
HP:0004798 |
| HPO |
HP:0005203 |
Spontaneous esophageal perforation |
"The occurrence of the full-thickness tear (perforation) of the wall of the esophagus." [HPO:probinson] |
Esophageal perforation can lead to retained gastric contents, saliva, bile, and other substances entering the mediastinum, resulting in mediastinitis, which in turn may lead to sepsis. |
HP:0002031 |
| HPO |
HP:0005206 |
Pancreatic pseudocyst |
"Cyst-like space not lined by epithelium and contained within the pancreas. Pancreatic pseudocysts are often associated with pancreatitis." [HPO:probinson] |
— |
HP:0012090 |
| HPO |
HP:0005207 |
Gastric hypertrophy |
"Hypertrophy of the stomach." [HPO:probinson] |
— |
HP:0002577 |
| HPO |
HP:0005208 |
Secretory diarrhea |
"Watery voluminous diarrhea resulting from an imbalance between ion and water secretion and absorption." [HPO:probinson] |
— |
HP:0002014 |