HPO
Db Link Name Definition Comment Is a
HPO HP:0005135 Abnormal T-wave "An abnormality of the T wave on the electrocardiogram, which mainly represents the repolarization of the ventricles." [HPO:probinson] HP:0003115
HPO HP:0005136 Mitral annular calcification "Mitral annular calcification (MAC) results from progressive calcium deposition along and beneath the mitral valve annulus." [HPO:probinson, PMID:23587525] MAC is a common degenerative process involving the fibrous annulus of the mitral valve, and is generally an incidental finding associated with aging. This term applies if MAC occurs at a substantially younger age than usual. HP:0004382
HPO HP:0005141 obsolete Episodes of ventricular tachycardia
HPO HP:0005143 Anomalous origin of right pulmonary artery from ascending aorta "The right pulmonary artery originates from the ascending aorta in the presence of a pulmonary valve and main pulmonary artery." [DDD:dbrown] HP:0011660
HPO HP:0005144 Ventricular septal hypertrophy "The dividing wall between left and right sides of the heart, thickens and bulges into the left ventricle." [http://www.heart.org/HEARTORG/Conditions/More/Cardiomyopathy/Hypertrophic-Cardiomyopathy_UCM_444317_Article.jsp#.WmePRJM-dL4, PMID:21349577] HP:0010438
HPO HP:0005145 Coronary artery stenosis "Abnormal narrowing of the coronary artery." [] HP:0006704
HPO HP:0005146 Cardiac valve calcification "Abnormal calcification of a cardiac valve." [HPO:probinson] HP:0001654, HP:0011915
HPO HP:0005147 Bidirectional ventricular ectopy HP:0006682
HPO HP:0005148 Pulmonary valve defects "Any defect in the valve connecting the heart and the pulmonary artery." [] HP:0001641
HPO HP:0005150 Abnormal atrioventricular conduction "An impairment of the electrical continuity between the atria and ventricles." [PMID:15372490] HP:0031546
HPO HP:0005151 Preductal coarctation of the aorta "Narrowing or constriction of the aorta localized proximal to the ductus arteriosus, i.e., to the preductal region of aortic arch." [DDD:dbrown] Blood flow to the aorta distal to the coarctation may be dependent on a patent ductus arteriosus, and hence closure of the ductus arteriosus can lead to serious ischemia of the affected tissues. HP:0012305
HPO HP:0005152 Histiocytoid cardiomyopathy "A type of cardiomyopathy characterized pathologically by hamartomatous lesions of cardiac Purkinje cells." [PMID:21585276, PMID:28050600] This HPO term intends to refer to the histological changes that characterize histiocytoid cardiomyopthy. The disease entity Histiocytoid cardiomyopathy is a rare arrhythmogenic disorder characterized by incessant ventricular tachycardia, cardiomegaly, and often sudden death by age 2 years. HP:0001638
HPO HP:0005155 Ventricular escape rhythm "A ventircular escape rhythm occurs whenever higher-lever pacemakers in AV junction or sinus node fail to control ventricular activation. Escape rate is usually 20-40 bpm, often associated with broad QRS complexes (at least 120 ms)." [] HP:0004308
HPO HP:0005156 Hypoplastic left atrium "Underdeveloped, small left heart atrium" [] HP:0025579
HPO HP:0005157 Concentric hypertrophic cardiomyopathy "Hypertrophic cardiomyopathy with an symmetrical and concentric pattern of hypertrophy." [HPO:probinson] HP:0001639
HPO HP:0005160 Total anomalous pulmonary venous return "Total anomalous pulmonary venous return refers to a congenital malformation in which all four pulmonary veins do not connect normally to the left atrium, but instead drain abnormally to the right atrium." [HPO:probinson] Pulmonary veins drain through abnormal connections to the right atrium. HP:0010772
HPO HP:0005162 Abnormal left ventricular function "Inability of the left ventricle to perform its normal physiologic function. Failure is either due to an inability to contract the left ventricle or the inability to relax completely and fill with blood during diastole." [http://www.heart.org/HEARTORG/Conditions/HeartFailure/AboutHeartFailure/Types-of-Heart-Failure_UCM_306323_Article.jsp#.WmeKyJM-dL4, PMID:10956313] HP:0030872
HPO HP:0005164 Dysplastic pulmonary valve "A congenital malformation of the pulmonary valve characterized by leaflet deformation." [PMID:7704986] HP:0001641
HPO HP:0005165 Shortened PR interval "Reduced time for the PR interval (beginning of the P wave to the beginning of the QRS complex). In adults, normal values are 120 to 200 ms long." [HPO:probinson] HP:0031593
HPO HP:0005168 Elevated right atrial pressure "An abnormal increase in magnitude of the pressure in the right atrium." [PMID:25211049] Elevated mean right atrial pressure (RAP) can be measured by cardiac catheterization. HP:0025443
HPO HP:0005170 Complete heart block with broad QRS complexes "A type of third degree heart block in which the escape rhythm arises at a relatively low part of the conduction system (below the atrioventricular node), which produces a wide QRS complex." [] HP:0001709
HPO HP:0005172 Left posterior fascicular block "Conduction block in the posterior division of the left bundle branch of the bundle of His." [HPO:probinson] HP:0011713
HPO HP:0005173 obsolete Calcific aortic valve stenosis
HPO HP:0005174 Membranous subvalvular aortic stenosis "Subvalvular stenosis is caused by a diaphragm-like membrane. The stenosis is clinically manifested like any other form of aortic stenosis but is often associated with some aortic insufficiency." [HPO:probinson, PMID:5817839] An important feature in the differential diagnosis between valvular and subvalvular aortic stenosis is the fact that no ejection sound is present in the latter. HP:0001682
HPO HP:0005176 Dysplastic aortic valve "A congenital malformation of the aortic valve characterized by leaflet deformation." [PMID:21349746] HP:0001646