| HPO |
HP:0410375 |
Increased proportion of naive CD4 T cells |
— |
An abnormally increased proportion of naive CD4 T cells relative to the total number of T cells. {xref="PMID:22474485"} |
HP:0031398, HP:0032219, HP:0410373 |
| HPO |
HP:0410376 |
Increased proportion of naive CD8 T cells |
"An abnormally increased proportion of naive CD8 T cells relative to the total number of T cells." [PMID:26700072] |
— |
HP:0031398 |
| HPO |
HP:0410377 |
Decreased proportion of naive CD8 T cells |
"An abnormally reduced proportion of naive CD8 T cells relative to the total number of T cells." [PMID:26700072] |
— |
HP:0031397 |
| HPO |
HP:0410378 |
Decreased proportion of naive CD4 T cells |
"An abnormally reduced proportion of naive CD4 T cells relative to the total number of T cells." [PMID:22474485] |
— |
HP:0410373 |
| HPO |
HP:0410379 |
Abnormal proportion of CD4-positive, alpha-beta memory T cells |
"An abnormal proportion of CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [CL:0000897] |
— |
HP:0031392, HP:0032182 |
| HPO |
HP:0410380 |
Abnormal proportion of CD8-positive, alpha-beta memory T cells |
"An abnormal proportion of CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. A CD8-positive, alpha-beta T cell with memory phenotype is CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [PMID:20146720, PMID:28481945] |
Human CD8+T cells are commonly classified into four subsets based on the surface expression of the leukocyte common antigen isoform CD45RA and the lymph node addressin CCR7. Thereby, naive TN cells (CD45RA+/CCR7+) are separated from central memory TCM (CD45RA-/CCR7+), effector memory TEM (CD45RA-/CCR7-) and TEMRA (CD45RA+/CCR7-) T cells. |
HP:0031393, HP:0032182 |
| HPO |
HP:0410381 |
Abnormal proportion of central memory CD4-positive, alpha-beta T cells |
"An abnormal proportion of central memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:22343568] |
— |
HP:0410379 |
| HPO |
HP:0410382 |
obsolete Abnormal proportion of effector memory CD4-positive, alpha-beta T cells |
— |
This term was a duplicate, hence it was obsoleted. https://github.com/obophenotype/human-phenotype-ontology/issues/5696 |
— |
| HPO |
HP:0410383 |
Abnormal proportion of effector memory CD8-positive, alpha-beta T cells |
"An abnormal proportion of effector memory CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410380 |
| HPO |
HP:0410384 |
Abnormal proportion of central memory CD8-positive, alpha-beta T cells |
"An abnormal proportion of central memory CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410380 |
| HPO |
HP:0410385 |
Decreased proportion of CD8-positive, alpha-beta memory T cells |
"Decreased proportion of CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. A CD8-positive, alpha-beta T cell with memory phenotype is CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [PMID:20146720] |
— |
HP:0032183 |
| HPO |
HP:0410386 |
Decreased proportion of CD4-positive, alpha-beta memory T cells |
"Decresaed proportion of CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [CL:0000897] |
— |
HP:0032183 |
| HPO |
HP:0410387 |
obsolete Decreased proportion of effector memory CD4-positive, alpha-beta T cells |
— |
This term was a duplicate, hence it was obsoleted. https://github.com/obophenotype/human-phenotype-ontology/issues/5696 |
— |
| HPO |
HP:0410388 |
Decreased proportion of central memory CD4-positive, alpha-beta T cells |
"A reduced proportion of central memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:22343568] |
An abnormally decreased proportion of central memory CD4+ T cells. These are memory cells that are located in the secondary lymphoid organs. These cells may have a CD3/CD4/CD62L+/CD45RA- phenotype. |
HP:0410386 |
| HPO |
HP:0410389 |
Decreased proportion of central memory CD8-positive, alpha-beta T cells |
"A reduced proportion of CD8-positive, alpha-beta central memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410384, HP:0410385 |
| HPO |
HP:0410390 |
Decreased proportion of effector memory CD8-positive, alpha-beta T cells |
"A reduced proportion of CD8-positive, alpha-beta effector memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410383, HP:0410385 |
| HPO |
HP:0410391 |
Increased proportion of CD4-positive, alpha-beta memory T cells |
"An abnormally elevated proportion of CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [CL:0000897] |
— |
HP:0032184, HP:0032219, HP:0410379 |
| HPO |
HP:0410392 |
Increased proportion of CD8-positive, alpha-beta memory T cells |
"An abnormally elevated proportion of CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [PMID:20146720] |
— |
HP:0032184, HP:0410380 |
| HPO |
HP:0410393 |
Increased proportion of central memory CD4-positive, alpha-beta T cells |
"An abnormally elevated proportion of central memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype of CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:22343568] |
These are memory cells that are located in the secondary lymphoid organs. These cells may have a CD3/CD4/CD62L+/CD45RA- phenotype. |
HP:0410391 |
| HPO |
HP:0410394 |
Increased proportion of effector memory CD4-positive, alpha-beta T cells |
"An abnormally elevated proportion of effector memory CD4-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:22343568] |
— |
HP:0410391 |
| HPO |
HP:0410395 |
Increased proportion of effector memory CD8-positive, alpha-beta T cells |
"An increased proportion of effector memory CD8-positive, alpha-beta T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410392 |
| HPO |
HP:0410396 |
Increased proportion of central memory CD8-positive, alpha-beta T cells |
"An increased proportion of central memory CD8-positive, alpha-beta T cells compared to the total number of T cells in the blood. These cells have the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [PMID:20146720, PMID:22343568] |
— |
HP:0410384, HP:0410392 |
| HPO |
HP:0410397 |
Bronchiolectasis |
"Saccular dilatation of the terminal bronchioles." [ORCID:0000-0002-8169-9049, PMID:20037680] |
— |
HP:0025426 |
| HPO |
HP:0410399 |
Positive blood lead test |
"Detection of lead in the blood." [] |
— |
HP:0410172 |
| HPO |
HP:0410400 |
Absent sebaceous glands |
"Absence of the sebaceous gland, the holocrine gland that secretes sebum into the hair follicles, or in hairless areas into ducts." [MP:0000647] |
— |
HP:0032226 |