HPO
Db Link Name Definition Comment Is a
HPO HP:0200041 Skin erosion "A discontinuity of the skin exhibiting incomplete loss of the epidermis, a lesion that is moist, circumscribed, and usually depressed." [HPO:skoehler] HP:0011355
HPO HP:0200042 Skin ulcer "A discontinuity of the skin exhibiting complete loss of the epidermis and often portions of the dermis and even subcutaneous fat." [HPO:skoehler] HP:0011355
HPO HP:0200043 Verrucae "Warts, benign growths on the skin or mucous membranes that cause cosmetic problems as well as pain and discomfort. Warts most often occur on the hands, feet, and genital areas." [HPO:skoehler] Cause is a virus called HPV (human papilloma virus), which infects the skin and causes the abnormal growth. There are many different varieties of the virus, which usually depends on the location of the lesion. HP:0012740
HPO HP:0200044 Porokeratosis "A clonal disorder of keratinization with one or multiple atrophic patches surrounded by a clinically and histologically distinctive hyperkeratotic ridgelike border called the cornoid lamella." [HPO:skoehler] HP:0011368
HPO HP:0200046 Cat cry "The presence of a characteristic high-pitched cry that sounds similar to the meowing of a kitten." [HPO:probinson] This unusual cry is characteristic of the cri du chat syndrome which results from a deletion on the p arm of chromosome 5. It is thought to be due to laryngeal hypoplasia, floppy epiglottis, small larynx, and asymmetric vocal cords, but is probably also related to dysfunction of the central nervous system. This sign occurs in infants and disappears with age. HP:0025429
HPO HP:0200047 Chondritis of pinna "Inflammation of the cartilage of the external ear." [HPO:probinson] HP:0000377, HP:0100662
HPO HP:0200048 Cyanotic episode HP:0000961
HPO HP:0200049 Upper limb hypertonia HP:0001446, HP:0002509
HPO HP:0200050 Bracket metacarpal epiphyses HP:0005913
HPO HP:0200053 Hemihypotrophy of lower limb "Shortening of a leg affecting only one side." [HPO:curators] HP:0100556
HPO HP:0200054 Foot monodactyly HP:0001849
HPO HP:0200055 Small hand "Disproportionately small hand." [HPO:probinson] HP:0005927
HPO HP:0200056 Macular scar "Scar tissue in the macula." [HPO:probinson] HP:0007401, HP:0100699
HPO HP:0200057 Marcus Gunn pupil "An aberrant pupillary response characterized by (i) Constriction of pupils of both eyes when the light stimulus is applied to the normal eye, and (ii) Dilatation of pupils of both eyes when the light stimulus is rapidly transferred from the normal eye (after brief light exposure to the normal eye) to the affected eye." [PMID:23520419, PMID:32491607] HP:0000587
HPO HP:0200058 Angiosarcoma HP:0030448
HPO HP:0200059 Metastatic angiosarcoma HP:0200058
HPO HP:0200063 Colorectal polyposis "Multiple abnormal growths that arise from the lining of the large intestine (colon or rectum) and protrude into the intestinal lumen." [] HP:0030255, HP:0100743
HPO HP:0200064 Asymmetry of iris pigmentation "Asymmetry between the two irides or asymmetry between different parts of one iris." [ORCID:0000-0003-0986-4123] HP:0008034
HPO HP:0200065 Chorioretinal degeneration HP:0000532
HPO HP:0200066 Ribbonlike corneal degeneration HP:0007705
HPO HP:0200067 Recurrent spontaneous abortion "Repeated episodes of abortion (Expulsion of the product of fertilization before completing the term of gestation) without deliberate interference." [HPO:probinson] HP:0005268
HPO HP:0200068 Nonprogressive visual loss HP:0000572
HPO HP:0200070 Peripheral retinal atrophy HP:0001105
HPO HP:0200071 Peripheral vitreoretinal degeneration "A type of vitreoretinal degeneration with manifestations that are concentrated at the periphery of the retina." [] HP:0007773
HPO HP:0200072 Episodic quadriplegia "Intermittent episodes of paralysis of all four limbs." [HPO:probinson] HP:0002445