| HPO |
HP:0012148 |
Multiple lineage myelodysplasia |
"Myelodysplasia with dysplastic changes in two or more of the myeloid lineages: erythroid, granulocytic, megakaryocytic." [DDD:akelly] |
— |
HP:0002863 |
| HPO |
HP:0012149 |
Bilineage myelodysplasia |
"Myelodysplasia with dysplastic changes in two of the myeloid lineages: erythroid, granulocytic, megakaryocytic." [DDD:akelly] |
— |
HP:0002863 |
| HPO |
HP:0012150 |
Single lineage myelodysplasia |
"Abnormality/dysplasia of a single myeloid cell (erythroid, granulocytic, or megakaryocytic)." [DDD:akelly] |
— |
HP:0002863 |
| HPO |
HP:0012151 |
Hemothorax |
"The presence of blood in the pleural space." [HPO:probinson] |
Hemothorax may result from hemorrhage in the chest wall, lung parenchyma, heart, or great vessels. |
HP:0002103 |
| HPO |
HP:0012152 |
Foveoschisis |
"Splitting of the retinal layers in the macula." [HPO:probinson] |
— |
HP:0000493, HP:0030502 |
| HPO |
HP:0012153 |
Hypotriglyceridemia |
"An decrease in the level of triglycerides in the blood." [HPO:probinson] |
— |
HP:0045014 |
| HPO |
HP:0012154 |
Anhedonia |
"Inability to experience pleasure activities usually found enjoyable." [HPO:probinson] |
— |
HP:0031466 |
| HPO |
HP:0012155 |
Decreased corneal sensation |
"Reduced ability of the cornea to respond to stimulation." [HPO:probinson] |
Corneal sensitivity to touch can be assessed by an aesthesiometer, which measures the corneal touch threshold. Decreased corneal sensation is associated with a decreased corneal reflex (HP:0008000); however, impairment of the corneal reflex can have other causes such as trigeminal nerve compression or a cerebellopontine angle lesion. Well known causes of decreased corneal sensation include Herpes simplex keratitis, neuroparalytic keratitis, leprosy, acoustic neuroma, and absolute glaucoma. |
HP:0000481 |
| HPO |
HP:0012156 |
Hemophagocytosis |
"Phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors in bone marrow and other tissues." [HPO:probinson] |
Hemophagocytosis is a nonspecific phenotypic feature observed in several conditions including hemolytic anemia, malignant disease, infections, and hemophagocytic syndrome (also known as hemophagocytic lymphohistiocytosis, a rare hyperinflammatory syndrome caused by severe hypercytokinemia due to a highly stimulated but ineffective immune process). |
HP:0004311 |
| HPO |
HP:0012157 |
Subcortical cerebral atrophy |
"Atrophy of the cerebral subcortical white and gray matter, termed subcortical atrophy, reflects loss of nerve cells in the basal ganglia or fibers in the deep white matter." [HPO:probinson, PMID:20813998] |
— |
HP:0007369 |
| HPO |
HP:0012158 |
Carotid artery dissection |
"A separation (dissection) of the layers of the carotid artery wall." [HPO:probinson] |
— |
HP:0005344 |
| HPO |
HP:0012159 |
Internal carotid artery dissection |
"A separation (dissection) of the layers of the internal carotid artery wall." [HPO:probinson] |
The internal carotid begins at the bifurcation of the common carotid, opposite the upper border of the thyroid cartilage, and runs perpendicularly upward. It supplies the anterior part of the brain, the eye and its appendages, and sends branches to the forehead and nose. Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the internal carotid artery and aneurysm formation. |
HP:0012158 |
| HPO |
HP:0012160 |
Intracranial internal carotid artery dissection |
"A separation (dissection) of the layers of the intracranial portion of the internal carotid artery wall." [HPO:probinson] |
— |
HP:0012159 |
| HPO |
HP:0012161 |
External carotid artery dissection |
"A separation (dissection) of the layers of the external carotid artery wall." [HPO:probinson] |
— |
HP:0012158 |
| HPO |
HP:0012162 |
Common carotid artery dissection |
"A separation (dissection) of the layers of the common carotid artery wall." [HPO:probinson] |
— |
HP:0012158 |
| HPO |
HP:0012163 |
Carotid artery dilatation |
"A dilatation (balooning or bulging out of the vessel wall) of a carotid artery." [HPO:probinson] |
— |
HP:0005344 |
| HPO |
HP:0012164 |
Asterixis |
"A clinical sign indicating a lapse of posture and is usually manifest by a bilateral flapping tremor at the wrist, metacarpophalangeal, and hip joints." [HPO:probinson] |
The examiner can test for asterixis by asking the patient to extend the arms, spread the fingers, dorsiflex the wrist and observe for the abnormal "flapping" tremor at the wrist. Asterixis represents the failure to actively maintain a position and is caused by the abnormal function of diencephalic motor centers that regulate the tone of the agonist and antagonist muscles involved in maintaining posture. |
HP:0100022 |
| HPO |
HP:0012165 |
Oligodactyly |
"A developmental defect resulting in the presence of fewer than the normal number of digits." [HPO:probinson] |
— |
HP:0011297 |
| HPO |
HP:0012166 |
Skin-picking |
"Repetitive and compulsive picking of skin which results in tissue damage." [HPO:probinson, PMID:20575652] |
— |
HP:0100716 |
| HPO |
HP:0012167 |
Hair-pulling |
"A phenomenon in which persons repetitively pull out their own hair, resulting in noticeable hair loss." [HPO:probinson] |
— |
HP:0100716 |
| HPO |
HP:0012168 |
Head-banging |
"Habitual striking of one's own head against a surface such as a mattress or wall of a crib." [HPO:probinson] |
— |
HP:0100716 |
| HPO |
HP:0012169 |
Self-biting |
"Habitual biting of one's own body." [HPO:probinson] |
Biting of one's own arms, lip, check, finger etc. |
HP:0100716 |
| HPO |
HP:0012170 |
Nail-biting |
"Habitual biting of one's own fingernails." [HPO:probinson] |
— |
HP:0012169 |
| HPO |
HP:0012171 |
Stereotypical hand wringing |
"Habitual clasping and squeezing of the hands." [HPO:probinson] |
— |
HP:0000733 |
| HPO |
HP:0012172 |
Stereotypical body rocking |
"Habitual repetitive movement of the body." [HPO:probinson] |
— |
HP:0000733 |