| HPO |
HP:0011443 |
Abnormality of coordination |
— |
— |
HP:0011442 |
| HPO |
HP:0011444 |
Decorticate rigidity |
"A type of rigidity in which the arms are in flexion and adduction and the legs are extended. This signifies a lesion in the cerebral white matter, internal capsules, or thalamus." [HPO:probinson] |
Decorticate posturing |
HP:0002063 |
| HPO |
HP:0011445 |
Athetoid cerebral palsy |
"A type of cerebral palsy characterized by slow, involuntary muscle movement and mixed muscle tone." [DDD:ssissodiya] |
Athetoid cerebral palsy is caused by damage to the basal ganglia. |
HP:0002071, HP:0100021 |
| HPO |
HP:0011446 |
Abnormality of higher mental function |
"Cognitive, psychiatric or memory anomaly." [DDD:ajackson] |
— |
HP:0012638 |
| HPO |
HP:0011447 |
Hyposegmentation of neutrophil nuclei |
"Hyposegmented (hypolobulated) or bilobed neutrophil nuclei." [DDD:probinson] |
Hyposegmented cells are neutrophils with fewer than three nuclear lobes. |
HP:0011992 |
| HPO |
HP:0011448 |
Ankle clonus |
"Clonus is an involuntary tendon reflex that causes repeated flexion and extension of the foot. Ankle clonus is tested by rapidly flexing the foot upward." [HPO:probinson] |
Ankle clonus is generally caused by corticospinal disease. |
HP:0002169, HP:0003028 |
| HPO |
HP:0011449 |
Knee clonus |
"Clonus is an involuntary tendon reflex that causes repeated flexion and extension of the foot. Knee clonus can be tested by rapidly pushing the patella towards the toes." [HPO:probinson] |
— |
HP:0002169 |
| HPO |
HP:0011450 |
Unusual CNS infection |
"A type of infection of the central nervous system that can be regarded as a sign of a pathological susceptibility to infection." [] |
— |
HP:0002011, HP:0032158 |
| HPO |
HP:0011451 |
Primary microcephaly |
"Head circumference below 2 standard deviations below the mean for age and gender at birth." [HPO:probinson] |
— |
HP:0000252 |
| HPO |
HP:0011452 |
Functional abnormality of the middle ear |
"An abnormality of the function of the middle ear." [HPO:probinson] |
The middle ear comprises the tympanic cavity in the temporal bone of the skull behind the eardrum, and is separated from the outer ear by the ear drum. The tympanic cavity contains the auditory ossicles (malleus, incus, stapes) that vibrate when exposed to sound, forming a chain that extends to the oval window of the inner ear and whose main function is to amplify sound. Additionally, the middle ear connects to the back of the throat and nose through the Eustachian tube. |
HP:0000370 |
| HPO |
HP:0011453 |
Abnormality of the incus |
"An abnormality of the incus, an ossicle in the middle ear." [DDD:dfitzpatrick] |
— |
HP:0004452 |
| HPO |
HP:0011454 |
Abnormality of the malleus |
"An abnormality of the malleus, an ossicle in the middle ear." [DDD:dfitzpatrick] |
— |
HP:0004452 |
| HPO |
HP:0011455 |
Absent malleus |
"Aplasia of the malleus." [DDD:dfitzpatrick] |
— |
HP:0011454 |
| HPO |
HP:0011456 |
Absent stapes |
"Aplasia of the stapes." [DDD:dfitzpatrick] |
— |
HP:0008628 |
| HPO |
HP:0011457 |
Loss of eyelashes |
"This term refers to the loss of eyelashes that were previously present." [HPO:probinson] |
Common causes of loss of eyelashes include inflammation, autoimmunity, tumors,endocrine disorders, drugs and medications, and a number of congenital conditions. |
HP:0000499 |
| HPO |
HP:0011458 |
Abdominal symptom |
"A subjective manifestation of disease localized to the abdomen." [] |
— |
HP:0025032 |
| HPO |
HP:0011459 |
Esophageal carcinoma |
"The presence of a carcinoma of the esophagus." [DDD:hfirth, NCIT:C3513] |
— |
HP:0100751 |
| HPO |
HP:0011460 |
Embryonal onset |
"Onset of disease at up to 8 weeks following fertilization (corresponding to 10 weeks of gestation)." [DDD:whouwehand] |
The time interval of a gestation is called the gestation period. In human obstetrics, gestational age refers to the fertilization age plus two weeks. This is approximately the duration since the woman's last menstrual period began. |
HP:0030674 |
| HPO |
HP:0011461 |
Fetal onset |
"Onset prior to birth but after 8 weeks of embryonic development (corresponding to a gestational age of 10 weeks)." [DDD:whouwehand] |
The time interval of a gestation is called the gestation period. In human obstetrics, gestational age refers to the fertilization age plus two weeks. This is approximately the duration since the woman's last menstrual period began. |
HP:0030674 |
| HPO |
HP:0011462 |
Young adult onset |
"Onset of disease at the age of between 16 and 40 years." [DDD:hfirth] |
— |
HP:0003581 |
| HPO |
HP:0011463 |
Childhood onset |
"Onset of disease at the age of between 1 and 5 years." [DDD:hfirth] |
This term refers to ages up to but not including the fifth birthday (see Juvenile onset). |
HP:0410280 |
| HPO |
HP:0011464 |
Aganglionosis of the small intestine |
"A lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) affecting the small intestine." [DDD:hfirth] |
— |
HP:0004362 |
| HPO |
HP:0011465 |
Duodenal aganglionosis |
"A lack of intestinal ganglion cells (i.e., an aganglionic section of bowel) affecting the duodenum." [DDD:hfirth] |
— |
HP:0011464 |
| HPO |
HP:0011466 |
Aplasia/Hypoplasia of the gallbladder |
"Absence or underdevelopment of the gallbladder." [HPO:probinson] |
— |
HP:0012437 |
| HPO |
HP:0011467 |
Absent gallbladder |
"A developmental defect in which the gallbladder fails to form." [DDD:hfirth] |
— |
HP:0011466 |