HPO
Db Link Name Definition Comment Is a
HPO HP:0000884 Prominent sternum HP:0000766
HPO HP:0000885 Broad ribs "Increased width of ribs" [HPO:probinson] HP:0000772
HPO HP:0000886 Deformed rib cage "Malformation of the rib cage." [HPO:probinson] HP:0001547
HPO HP:0000887 Cupped ribs "Wide, concave rib end." [HPO:probinson] HP:0000772
HPO HP:0000888 Horizontal ribs "A horizontal (flat) conformation of the ribs, the long curved bones that form the rib cage and normally progressively oblique (slanted) from ribs 1 through 9, then less slanted through rib 12." [HPO:probinson] HP:0000772
HPO HP:0000889 Abnormal clavicle morphology "Any abnormality of the clavicles (collar bones)." [HPO:probinson] HP:0000765
HPO HP:0000890 Long clavicles "Increased length of the clavicles." [HPO:probinson] HP:0000889
HPO HP:0000891 Cervical ribs HP:0005815
HPO HP:0000892 Bifid ribs "A bifid rib refers to cleavage of the sternal end of a rib, usually unilateral. Bifid ribs are usually asymptomatic, and are often discovered incidentally by chest x-ray." [HPO:probinson] HP:0000772
HPO HP:0000893 Bulging of the costochondral junction "Abnormal outward curving (protuberance) of the junction of ribs and costal cartilage." [HPO:probinson] The costochondral junction is the structure where the ribs articulate with the sternum. HP:0000766, HP:0000919
HPO HP:0000894 Short clavicles "Reduced length of the clavicles." [HPO:probinson] HP:0006710
HPO HP:0000895 Lateral clavicle hook "An excessive upward convexity of the lateral clavicle." [HPO:probinson, PMID:7322653] HP:0000889
HPO HP:0000896 Rib exostoses "Multiple circumscribed bony excrescences located in the ribs." [HPO:probinson] HP:0000772, HP:0100777
HPO HP:0000897 Rachitic rosary "A row of beadlike prominences at the junction of a rib and its cartilage (i.e., enlarged costochondral joints), resembling a rosary." [HPO:probinson, PMID:26745253] Nutritional rickets (NR), secondary to vitamin D deficiency and/or dietary calcium deficiency, is characterized by a range of features including 1) hypocalcemic seizures and tetanic spasms; 2) life-threatening hypocalcemic cardiomyopathy; 3) bone pain and muscle weakness; 4) limb and pelvic deformities; 5) failure to thrive; 6) developmental delay; and 7) dental anomalies. Rickets can additionally be caused by genetic defects such as a defect in the vitamin D receptor gene. HP:0000766, HP:0000919
HPO HP:0000900 Thickened ribs "Increased thickness (diameter) of ribs." [HPO:probinson] HP:0000772
HPO HP:0000902 Rib fusion "Complete or partial merging of adjacent ribs." [HPO:probinson] HP:0000772
HPO HP:0000904 Flaring of rib cage "The presence of wide, concave anterior rib ends." [HPO:curators] HP:0000772
HPO HP:0000905 Progressive clavicular acroosteolysis "Progressive bone resorption in the distal part of the clavicle." [HPO:probinson] HP:0000889, HP:0002797
HPO HP:0000907 Anterior rib cupping "Wide, concave anterior rib end." [HPO:probinson] HP:0000887
HPO HP:0000910 Wide-cupped costochondral junctions HP:0000919
HPO HP:0000911 Flat glenoid fossa "Abnormally flat configuration of the glenoid fossa, also known as the glenoid cavity, which is the articular surface of the scapula that articulates with the head of the humerus." [HPO:probinson, PMID:15163819] See PMID:15163819, figure 2, for the arthrographic appearance of a flat glenoid fossa. HP:0011912
HPO HP:0000912 Sprengel anomaly "A congenital skeletal deformity characterized by the elevation of one scapula (thus, one scapula is located superior to the other)." [HPO:probinson] Sprengel deformity is associated with malposition and dysplasia of the scapula and also involves regional muscle hypoplasia or atrophy, which causes disfigurement and limitation of shoulder movement. Sprengel deformity may be unilateral or bilateral and occur in isolation or as a syndromic component. Abduction of shoulder beyond 90 degrees is impossible. HP:0000782
HPO HP:0000913 Posterior rib fusion "Complete or partial merging of the posterior part of adjacent ribs." [HPO:probinson] HP:0000902
HPO HP:0000914 Shield chest "A broad chest." [HPO:probinson, PMID:22368597] Stretching of the thoracic cage as a result of fetal edema may contribute to the shield chest with widely spaced nipples that can be obsered in persons with Turner syndrome. HP:0100625
HPO HP:0000915 Pectus excavatum of inferior sternum "Pectus excavatum (defect of the chest wall characterized by depression of the sternum) affecting primarily the inferior region of the sternum." [HPO:probinson] HP:0000767