| HPO |
HP:0005365 |
Severe B lymphocytopenia |
"A severe form of B lymphocytopenia in which the count of B cells is very low or absent." [HPO:probinson] |
— |
HP:0010976 |
| HPO |
HP:0005366 |
Recurrent streptococcus pneumoniae infections |
"Increased susceptibility to streptococcus pneumoniae infections as manifested by a history of recurrent infections by streptococcus pneumoniae." [HPO:probinson] |
— |
HP:0002205, HP:0020096 |
| HPO |
HP:0005368 |
Abnormality of humoral immunity |
"An abnormality of the humoral immune system, which comprises antibodies produced by B cells as well as the complement system." [HPO:probinson] |
— |
HP:0010978 |
| HPO |
HP:0005369 |
Decreased serum complement factor H |
"A reduced level of the complement component Factor H in circulation." [https://emedicine.medscape.com/article/135478-overview] |
— |
HP:0004431 |
| HPO |
HP:0005372 |
Abnormality of B cell physiology |
"An abnormality of the physiological functioning of B cells." [HPO:probinson] |
This term refers to any abnormality of the B cells, which play a role in the humoral immune response. The main functions of B cells are to produce antibodies, to perform the role of antigen presenting cells, and to develop into memory cells. |
HP:0031409 |
| HPO |
HP:0005374 |
Cellular immunodeficiency |
"An immunodeficiency characterized by defective cell-mediated immunity or humoral immunity." [http://www.dictionary.com/browse/cellular-immunodeficiency] |
— |
HP:0002721 |
| HPO |
HP:0005375 |
obsolete Partial cellular immunodeficiency |
— |
— |
— |
| HPO |
HP:0005376 |
Recurrent Haemophilus influenzae infections |
"Increased susceptibility to Haemophilus influenzae infections as manifested by recurrent episodes of infection by Haemophilus influenzae." [HPO:probinson] |
— |
HP:0005420 |
| HPO |
HP:0005379 |
obsolete Severe T lymphocytopenia |
— |
— |
— |
| HPO |
HP:0005381 |
Recurrent meningococcal disease |
"Recurrent infections by Neisseria meningitidis (one of the most common causes of bacterial meningitis), which is also known as meningococcus." [HPO:curators] |
— |
HP:0005430 |
| HPO |
HP:0005384 |
Defective B cell activation |
"A reduced ability of a B cell to become activated, i.e., the change in morphology and behavior of" [GOC:mgi_curators, ISBN:0781735149] |
— |
HP:0005372 |
| HPO |
HP:0005386 |
Recurrent protozoan infections |
"Increased susceptibility to protozoan infections, as manifested by recurrent episodes of protozoan infection." [HPO:probinson] |
— |
HP:0002719 |
| HPO |
HP:0005387 |
Combined immunodeficiency |
"A group of phenotypically heterogeneous genetic disorders characterized by profound deficiencies of T- and B-cell function, which predispose the patients to both infectious and noninfectious complications." [PMID:23321211] |
— |
HP:0002721 |
| HPO |
HP:0005389 |
Depletion of components of the alternative complement pathway |
"An abnormal reduction in the components of the alternative complement pathway, such as the C3 protein or its cleavage products." [https://en.wikipedia.org/wiki/Alternative_complement_pathway] |
— |
HP:0005482 |
| HPO |
HP:0005390 |
Recurrent opportunistic infections |
"Increased susceptibility to opportunistic infections, as manifested by recurrent episodes of infection by opportunistic agents, i.e., by microorganisms that do not usually cause disease in a healthy host, but are able to infect a host with a compromised immune system." [HPO:probinson] |
— |
HP:0002719, HP:0031690 |
| HPO |
HP:0005396 |
Susceptibility to coronavirus 229e |
"Increased susceptibility to coronavirus 229e, as manifested by recurrent episodes of coronavirus 229e." [] |
— |
HP:0004429 |
| HPO |
HP:0005397 |
obsolete Exaggerated cellular immune processes |
— |
— |
— |
| HPO |
HP:0005400 |
Reduction of neutrophil motility |
"An abnormal reduction of the cell motility of neutrophils." [HPO:probinson] |
— |
HP:0011990 |
| HPO |
HP:0005401 |
Recurrent candida infections |
"An increased susceptibility to candida infections, as manifested by a history of recurrent episodes of candida infections." [HPO:probinson] |
— |
HP:0002841 |
| HPO |
HP:0005402 |
obsolete Primary T-lymphocyte immune abnormalities |
— |
— |
— |
| HPO |
HP:0005403 |
T lymphocytopenia |
"An abnormally low count of T cells." [HPO:probinson] |
— |
HP:0001888, HP:0011839 |
| HPO |
HP:0005404 |
Increased B cell count |
"An abnormal increase from the normal count of B cells." [HPO:probinson] |
— |
HP:0010975, HP:0100827 |
| HPO |
HP:0005406 |
Recurrent bacterial skin infections |
"Increased susceptibility to bacterial infections of the skin, as manifested by recurrent episodes of infectious dermatitis." [HPO:probinson] |
Infectious dermatitis may manifest as impetigo, multiple purulent blisters, erythema, lymphadenopathy near the site of infection. |
HP:0001581, HP:0002718 |
| HPO |
HP:0005407 |
Decreased proportion of CD4-positive helper T cells |
"A decreased proportion of circulating CD4-positive helper T cells relative to total T cell count." [HPO:probinson] |
— |
HP:0005403, HP:0032218, HP:0500267 |
| HPO |
HP:0005409 |
obsolete Markedly reduced T cell function |
— |
— |
— |